Abstract Background The mechanisms by which glia respond to viral central nervous system (CNS) pathogens are now becoming apparent with the demonstration that microglia and astrocytes express an array of pattern recognition receptors that include intracellular RNA and DNA sensors.We have previously demonstrated that glia express Z-DNA binding prote
Castrate-resistant prostate cancer (CRPC) is the lethal form of prostate cancer.Epithelial mesenchymal plasticity (EMP) has been associated with disease progression to CRPC, and prostate cancer therapies targeting the androgen signalling axis, including androgen deprivation therapy (ADT), promote EMP.We explored effects of castration on Fiction and
The quest for happiness is highly esteemed in every culture.Based on the theory of the positive activity model, the current study examined the role of psychological hardiness in happiness among youth.The study also investigated the parallel mediating role of vitality and materialistic values in the relationship between psychological hardiness Liqui
Standing on the west bank of the Ping river in northern Thailand, Baan Fai Rim Ping displayed a fluid profile of multiple perspective points.Such an eccentric appearance, Fiction and Literature however, belied the senses of place and historical continuity, along with the feeling of belonging provided by this waterfront residence.Apart from occupyin
Timber buildings might incur damages after a long service, because column foot damage affects the structural performance under the continued use.In this paper, six straight-tenon joint wood frame specimens were prepared with varying degrees of two different damage conditions at a scale of 1 : 3.52.To obtain failure mode and hysteresis performance o